Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro

Article ID	Journal	Published Year	Pages	File Type
5820872	International Journal of Pharmaceutics	2012	8 Pages	PDF

Keywords

FBS PKPD ASP+NHBE TEER HBSS RT-PCR GAPDH FITC HEPES DMSO Ali normal human bronchial epithelial Bronchial epithelium Oct Tetraethylammonium Pulmonary absorption Carrier-mediated transport dimethyl sulphoxide air–liquid interface foetal bovine serum Calu-3 cells Pharmacokinetic/pharmacodynamic fluorescein isothiocyanate Hank's balanced salt solution In vitro models transepithelial electrical resistance Permeability reverse transcriptase polymerase chain reaction Papp TEA Organic cation transporters glyceraldehyde-3-phosphate dehydrogenase

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science

Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro

Authors

Manali Mukherjee, D.I. Pritchard, C. Bosquillon,