| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5821276 | International Journal of Pharmaceutics | 2011 | 9 Pages |
Abstract
LNCs did not cause hearing loss, cell death, and changes of synaptophysin, ribbon synapses, and S-100. But a neurofilament decrease was observed in SGC and cochlear nerve.
Keywords
TRITCPBSLNCsneurofilament-200FITCNF-200DAPIABRSNHLSGCsOHC4,6-diamidino-2-phenylindoleRWM molecular pathologyIsothiocyanateIHCtetramethylrhodamine isothiocyanateCochleaOuter hair cellsinner hair cellsspiral ganglion cellsToxicityRound Window MembranePhosphate buffered salineRatNanoparticlesauditory brainstem responsesensorineural hearing loss
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Authors
Ya Zhang, Weikai Zhang, Marian Löbler, Klaus-Peter Schmitz, Patrick Saulnier, Thomas Perrier, Ilmari Pyykkö, Jing Zou,