The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARÎ³ ligands

Article ID	Journal	Published Year	Pages	File Type
5823148	Biochemical Pharmacology	2016	14 Pages	PDF

Keywords

RSV caspase-activated deoxyribonuclease TMS MDA tetramethylsilane RGZ HR-ESI-MS RXR Retinoid X receptor PPARγ TCF PBS LBD PPARs ROS TZDs PPRE phosphate saline buffer Surface plasmon resonance SPR Apoptosis ligand-binding domain Docking rosiglitazone Colorectal cancer Colorectal cancer cells CAD T-cell factor PPAR response element malondialdehyde Rous sarcoma virus CRC Reactive oxygen species Peroxisome proliferator-activated receptors peroxisome proliferator-activated receptor γ

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Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

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The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARÎ³ ligands

Authors

Diana Zurlo, Pamela Ziccardi, Carolina Votino, Tommaso Colangelo, Carmen Cerchia, Fabrizio Dal Piaz, Sabrina Dallavalle, Salvatore Moricca, Ettore Novellino, Antonio Lavecchia, Vittorio Colantuoni, Angelo Lupo,