| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5823291 | Biochemical Pharmacology | 2015 | 45 Pages |
Abstract
Nitrobenzoxadiazoles exert antitumor effects against vemurafenib-resistant melanoma cells by sustained activation of different MAPK pathways.
Keywords
(MAPK)JnkMBPSulphorhodamine BGSTnitrobenzoxadiazoleMAPK phosphatases(ERK)NBDBRAFc-Jun N-terminal kinasecolony formation assayMelanomaTNF receptor-associated factor 2body weightVemurafenibmultidrug resistance-associated proteinsmitogen activated protein kinaseextracellular signal-regulated kinaseapoptosis signal-regulating kinase 1Glutathione transferase
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Authors
Grazia Graziani, Simona Artuso, Anastasia De Luca, Alessia Muzi, Dante Rotili, Manuel Scimeca, Maria Grazia Atzori, Claudia Ceci, Antonello Mai, Carlo Leonetti, Lauretta Levati, Elena Bonanno, Lucio Tentori, Anna Maria Caccuri,