Article ID Journal Published Year Pages File Type
5823350 Biochemical Pharmacology 2014 11 Pages PDF
Abstract
Even though the hydrophilicity of second-generation antihistamines is generally increased, entropy-dependent hydrophobic interaction was more important in their binding to human histamine H1 receptors.
Keywords
Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
Preview
Differential thermodynamic driving force of first- and second-generation antihistamines to determine their binding affinity for human H1 receptors
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