| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5823526 | Biochemical Pharmacology | 2013 | 9 Pages |
Abstract
PDA-66 hinders proliferation of human progenitor and cancer cells by destabilising microtubules, leading to mitotic arrest and apoptosis. Thus indolylmaleimides provide a class of indoles to be used as anti-mitotic drugs.
Keywords
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Pharmacology
Authors
Christian Eisenlöffel, Anne-Caroline Schmöle, Anahit Pews-Davtyan, Anne Brennführer, Sergei A. Kuznetsov, Rayk Hübner, Stefanie Frech, Catrin Schult, Christian Junghanss, Matthias Beller, Arndt Rolfs, Moritz J. Frech,