Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5823975 | Biochemical Pharmacology | 2011 | 9 Pages |
Abstract
TH-4-PX inhibited LPS-induced iNOS expression by interference with the posttranslational modification of IRAK-1 resulted in blocking TAK1-mediated activation of IKK and MAPKs signal transduction to down-regulate NF-κB and AP-1 activation.
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Wen-Fei Chiou, Chien-Chih Chen, I.-Hsin Lin, Jen-Hwey Chiu, Yi-Ju Chen,