Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5824057 | Biochemical Pharmacology | 2011 | 9 Pages |
Abstract
In baboons, the major enzyme responsible for hydroxylation of bupropion belongs to the CYP 2B subfamily of enzymes. The formation of the reduced metabolites is catalyzed by carbonyl reducing enzymes.
Keywords
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Authors
Xiaoming Wang, Doaa R. Abdelrahman, Valentina M. Fokina, Gary D.V. Hankins, Mahmoud S. Ahmed, Tatiana N. Nanovskaya,