Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5824064 | Biochemical Pharmacology | 2010 | 9 Pages |
Abstract
Phenotypic screening of the LOPAC library identified several potent and selective inhibitors of African trypanosomes. The κ-opioid agonist (+)-U50,488 represents a novel lead for drug discovery against sleeping sickness.
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Authors
Deuan C. Jones, Irene Hallyburton, Laste Stojanovski, Kevin D. Read, Julie A. Frearson, Alan H. Fairlamb,