| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5824138 | Biochemical Pharmacology | 2011 | 10 Pages |
Abstract
ABC50 promotes the association of Met-tRNA with the eIF2 complex. eIF2α represents a key initiation control point. In response to cellular stress of various kinds, eiF2α is phosphorylated by key kinases which suppress translation initiation. ABC50 promotes the association of Met-tRNA with eIF2, enhancing translation.
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Authors
Yongmao Yu, Yicheng Zhang, Ziping Zhu, Stuart A. Berger,