| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5830849 | Fitoterapia | 2014 | 6 Pages |
Abstract
Three new steroidal saponins, named diospreussinosides A-C (1-3), along with two known ones (4, 5) were isolated from rhizomes of Dioscorea preussii. The spirostane-type skeleton of compound 3 with an unusual dihydroxylation pattern on the F-ring is reported for the first time. Cytotoxicity of 2-5 was evaluated against two human colon carcinoma cell lines (HT-29 and HCT 116). The most active compound was a derivative of pennogenin (5).92
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Authors
Turibio Kuiate Tabopda, Anne-Claire Mitaine-Offer, Chiaki Tanaka, Tomofumi Miyamoto, Jean-François Mirjolet, Olivier Duchamp, Bonaventure Tchaleu Ngadjui, Marie-Aleth Lacaille-Dubois,