| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5830870 | Fitoterapia | 2014 | 6 Pages |
Abstract
Three new metabolites (compounds 1-2 and 6), one azaphilone, and two meroterpenes, together with eleven known compounds have been isolated from a mangrove endophytic fungus, Penicillium 303#. Structure elucidation was achieved by 1D and 2D NMR spectroscopy. The absolute configurations of 1 and 2 were determined by electronic circular dichroism (ECD). Cytotoxic activities of new compounds 1-2 and 6 and compound 7were evaluated in vitro against human cancer lines MDA-MB-435, HepG2, HCT-116, and A549. Those compounds showed weak to moderate cytotoxic activities.
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Authors
Jing Li, Xin Yang, Yingying Lin, Jie Yuan, Yongjun Lu, Xun Zhu, Jun Li, Mengfeng Li, Yongcheng Lin, Jianguo He, Lan Liu,