Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5830873 | Fitoterapia | 2014 | 6 Pages |
Abstract
Two new steroidal esters with an unusual framework, Sinkiangenorin A and B, a new organic acid glycoside, Sinkiangenorin C, and four known lignin compounds were isolated from the seeds of Ferula sinkiangensis. The structures of these compounds were established by spectroscopic analysis and single-crystal X-ray diffraction. All of the isolated compounds were tested against Hela, K562 and AGS human cancer cell lines. Sinkiangenorin C showed cytotoxic activity against AGS cells with an IC50 of 36.9 μM.
Graphical abstractDownload high-res image (78KB)Download full-size image
Keywords
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Guangzhi Li, Xiaojin Li, Li Cao, Liangang Shen, Jun Zhu, Jing Zhang, Junchi Wang, Lijing Zhang, Jianyong Si,