| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5830951 | Fitoterapia | 2013 | 4 Pages |
Abstract
A new cembrane diterpene, named (â)-(1S)-15-hydroxy-18-carboxycembrene, was isolated from petroleum ether extract of the roots of the Euphorbia pekinensis Rupr. To our knowledge, this compound is the first cembrane-type diterpenoid to be found in the family Euphorbiaceae. The structure was elucidated as (â)-(1S)-15-hydroxy-cembra -2E, 4Z, 7E, 11E-tetraen-18-oic acid by a combination of IR, HR-ESIMS, 1D- and 2D-NMR techniques. (â)-(1S)-15-hydroxy-18-carboxycembrene showed cytotoxic activity against all five human cancer cell lines tested.
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Authors
Pengyi Hou, Yan Zeng, Bingjie Ma, Kaishun Bi, Xiaohui Chen,