Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5831009 | Fitoterapia | 2013 | 7 Pages |
Abstract
Four new flavonoids including three C-glycosidic flavonoids, named tetrastigma A-D (1-4) and five known flavones (5-9) were isolated from the herbs of Tetrastigma obtectum (Wall.) Planch. The structures of 1-4 were elucidated by 1D- and 2D-NMR and HR mass spectrometric methods. Compound 1 caused significant enhancement in glucose consumption by insulin-resistant HepG2 cells compared with control cells. In addition, compound 1 stimulated phosphorylation of AMPK, which plays an important role in glycometabolism.
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Authors
Mei-Na Jin, Guo-Ru Shi, Sheng-An Tang, Nan-Qin Nan-Qin, Wei Qiao, Hong-Quan Duan,