| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5831025 | Fitoterapia | 2014 | 12 Pages |
Abstract
Isoangustone A derived from licorice induces apoptosis in colorectal cancer cells by inducing mitochondrial outer membrane permeabilization, inhibited Akt phosphorylation and activated AMPK.237
Keywords
IAApoly [ADP-ribose] polymerase 1DR4MPTDCFH-DAAMPKmTORPTPCIMSPARP-1FBSPI3KMitochondria permeability transitionAMP-activated protein kinaseBSAMTTmitochondrial outer membrane permeabilizationbovine serum albuminTemApoptosisdichlorofluorescin diacetateelectron transport chainColorectal cancerfetal bovine serumphosphoinositide 3-kinaseintermembrane spaceTRAILTNF-related apoptosis-inducing ligandMOMPpermeability transition pore complexTransmission electron microscopymammalian target of rapamycinETcPropidium iodideDeath receptor 4
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Authors
Wei Huang, Shunan Tang, Xue Qiao, Wanwan Ma, Shuai Ji, Kui Wang, Min Ye, Siwang Yu,