Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5831480 | Fitoterapia | 2012 | 7 Pages |
A new chlorinated flavonoid, 3, 6, 8-trichloro-5, 7, 3â², 4â²-tetrahydroxyflavone (1), a new biscoumaric acid derivative, 4-O-(2â³, 3â³-O-diacetyl-6â³-O-p-coumaroyl-β-d-glucopyranosyl)-p-coumaric acid (2), and 8, 3â², 4â²-trihydroxyflavone-7-O-β-d-glucopyranoside (3) together with twenty-four known compounds (4-27) were isolated from the whole plant of Bidens bipinnata. All chemical structures were established on the basis of UV-, MS- and NMR (1H, 13C, 1H-1H COSY, HMQC and HMBC) spectroscopic data. Some of the isolated compounds were tested for the inhibition of α-amylase. The result showed that isookanin (6) was a potent inhibitor of α-amylase (IC50 = 0.447 mg/ml).
Graphical abstractA new chlorinated flavonoid, 3, 6, 8-trichloro-5, 7, 3â², 4â²-tetrahydroxyflavone (1), a new biscoumaric acid derivative, 4-O-(2â³, 3â³-O-diacetyl-6â³-O-p-coumaroyl β-d-glucopyranosyl)-p-coumaric acid (2), and 8, 3â², 4â²-trihydroxyflavone-7-O-β-d-glucopyranoside (3) together with twenty-four known compounds (4-27) were isolated from the whole plant of Bidens bipinnata. Some of the isolated compounds were tested for the inhibition of α-amylase.Download high-res image (96KB)Download full-size image