Bioactivity-integrated UPLC/Q-TOF-MS of Danhong injection to identify NF-ÎºB inhibitors and anti-inflammatory targets based on endothelial cell culture and network pharmacology

Article ID	Journal	Published Year	Pages	File Type
5834730	Journal of Ethnopharmacology	2015	17 Pages	PDF

Keywords

IκB qPCR ESI BCR DSS SAC TCr NF-kB Bcl-2 SAB SOS1 FAK HEK293 IKK HSYA SAA Danshensu CHM NF-kappa B Salvianolic acid C ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry PI3K FBS DEX NF-κB PBS IL-6 DMEM MTT PCA Photodiode array detector Akt salvianolic acid A Salvianolic acid B protocatechuic acid interleukin-6 Bax dHI coronary artery disease analysis of variance Danhong injection ELISA Enzyme-linked immunosorbent assay tumor necrosis factor-alpha standard error mean Chinese herbal medicines Dexamethasone fetal bovine serum Anti-inflammatory CAD Network pharmacology Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)TNF-α phosphate buffer saline phosphorylated lactate dehydrogenase LDH B-cell lymphoma-2 Dulbecco’s modified eagle’s medium SEM inhibitor of nuclear factor kappa-B kinase inhibitor of NF-κB Hydroxysafflor yellow A quantitative real-time PCR Bcl-2 Associated X protein protein kinase B protocatechuic aldehyde Caffeic acid human embryonic kidney 293 focal adhesion kinase electrospray ionization

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

Bioactivity-integrated UPLC/Q-TOF-MS of Danhong injection to identify NF-ÎºB inhibitors and anti-inflammatory targets based on endothelial cell culture and network pharmacology

Authors

Xiaoqing Jiang, Bin Lv, Pan Li, Xianghui Ma, Ting Wang, Qian Zhou, Xiaoying Wang, Xiumei Gao,