Myrsine seguinii ethanolic extract and its active component quercetin inhibit macrophage activation and peritonitis induced by LPS by targeting to Syk/Src/IRAK-1

Article ID	Journal	Published Year	Pages	File Type
5836726	Journal of Ethnopharmacology	2014	10 Pages	PDF

Keywords

TAK1 AP-1 TLR IKK PGE2 iNOS ERK RT-PCR ATF2 MAP kinase kinase MYD88 Jnk COX LPS (TNF)-α PI3K NF-κB CREB c-Jun N-terminal kinase IκBα kinase MAPK MKK MTT inducible NO synthase TRIF cyclooxygenase Akt Anti-inflammatory effects cAMP response element-binding enzyme immunoassay EIA TIR-domain-containing adapter-inducing interferon-β Syk tumour necrosis factor-α spleen tyrosine kinase tumour necrosis factor IRAK-1 nuclear factor-κB phosphoinositide 3-kinase activating transcription factor 2 lipopolysaccharide Nitric oxide Reverse transcriptase-polymerase chain reaction activator protein-1 protein kinase B mitogen-activated protein kinase Prostaglandin E2 Quercetin extracellular signal-related kinase Interleukin-1 receptor-associated kinase-1 Toll-like receptors (TLR)

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

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Myrsine seguinii ethanolic extract and its active component quercetin inhibit macrophage activation and peritonitis induced by LPS by targeting to Syk/Src/IRAK-1

Authors

Woo Seok Yang, Deok Jeong, Young-Su Yi, Byoung-Hee Lee, Tae Woong Kim, Khin Myo Htwe, Young-Dong Kim, Kee Dong Yoon, Sungyoul Hong, Woo-Shin Lee, Jae Youl Cho,