| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5837056 | Journal of Ethnopharmacology | 2013 | 6 Pages |
Abstract
Antioxidant and anti-inflammatory activities of extracts and subfractions of P. recta herb in in vitro systems together with their chemical composition were examined. The highest scavenging activity against DPPH, H2O2, HClO, and the strongest inhibition of lipoxidase and hyaluronidase activity was observed for ethyl acetate subfraction from which compound responsible for the activity, ellagitannin-agrimoniin was isolated. The compound was responsible for reactive oxygen species scavenging and enzyme inhibition activity.267
Keywords
NaClOHRPIC50NBTASAHPLC-DAD-MSLTB4HPTLCHPRTNBDPPHNaBH4FeCl3ESIAgrimoniinHPLC-DAD-MSnHClOUV-VisPBSDTNB, 5nitrobluetetrazoliumHHDPnuclear magnetic resonanceO2•−ROSHydrogen peroxideAscorbic acidAntioxidantsuperoxide anion5-thio-2-nitrobenzoic acidLinoleic acidhypochlorous acidLOXSodium borohydrideNMRStandard error of measurementSodium hypochloriteAnti-inflammatoryaqueous extracthydroethanolic extractpreLeukotriene B4LipoxidasePhosphate-buffered salineSEMhalf maximal inhibitory concentrationHeparinHyalHyaluronidaseH2O2Horseradish peroxidasehigh-performance thin layer chromatographyQuercetinReactive oxygen specieselectrospray ionization
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Authors
Agnieszka Bazylko, Jakub P. Piwowarski, Agnieszka Filipek, Jessica Bonarewicz, MichaÅ Tomczyk,