| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5838035 | Journal of Ethnopharmacology | 2012 | 14 Pages |
Abstract
Phenol-enriched extracts of four Bauhinia species namely Bauhinia bowkeri, Bauhinia galpinii, Bauhinia petersiana and Bauhinia variegata used as antidiarrhoeal therapies in South African traditional medicine were evaluated against factors associated with diarrhoea. All the crude extracts and their fractions of varied polarities have good activity against one or more diarrhoeal factors. However, the extracts need to be used with caution due to selective COX-1 inhibitory activity and the cytotoxicity potential against Vero cell lines.152
Keywords
NRFAT2IC50FRAPTLCBAVAlCl3LPOdpmGITBAPMICATCCNaHCO3PVPPIBDLC50TEACEC50intGAERNSARMAb2A02Potassium persulphateBauhinia variegataPBSCOXSDSDCMHClFLLDPPHBuOHNCCLsEtOAc2, 2-diphenyl-1-picrylhydrazylDMSODNAMTTROSEthyl acetateDiarrhoeadeoxyribose nucleic acidhydrochloric acidLOXButanolBauhiniairritable bowel diseaseanalysis of varianceANOVAAbsorbanceminimal essential mediumstandard errorOral rehydration therapyGastrointestinal tractdimethyl sulphoxideDichloromethaneCarbon dioxideCyanidin-3-glucosideCytotoxicityAnti-inflammatoryTrolox equivalent antioxidant capacitydilution factorPotassium ferrocyanidePotassium ferricyanideBABFlavonolPhenolicslipoxygenaseAntimicrobialMEMAmerican Type Culture CollectionORTphosphate buffer solutionGallic acid equivalentcatechin equivalentquercetin equivalentmilligramhydroxylLipid peroxidationprostaglandinpolyvinylpolypyrrolidoneferric reducing antioxidant powerCO2Sodium hydrogen carbonateTLC, Thin layer chromatographyTotal flavonoidtotal phenolicAluminium chlorideNational Committee for Clinical Laboratory StandardsBagGallotanninreactive nitrogen speciesReactive oxygen species
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Authors
Aroke S. Ahmed, Esameldin E. Elgorashi, Nivan Moodley, Lyndy J. McGaw, Vinasan Naidoo, Jacobus N. Eloff,