| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5838108 | Journal of Ethnopharmacology | 2013 | 6 Pages |
Abstract
Picrasma quassiodes (D. Don) Benn. is a widely used herbal medicine for treatment of gastroenteritis, eczema, hypertension and other diseases. Our study showed that the extract from Picrasma quassiodes (D. Don) Benn. had an antihypertensive effect on spontaneously hypertensive rats, the mechanism included reducing activity of superoxide dismutase, increasing the expression of endothelial nitric oxide synthase (eNOS), which regulated nitric oxide (NO) and relaxed blood vessels. 329
Keywords
MBPMDAeNOSiNOSNOSDBPSBPPBSMPOH&EANOVAone-way analysis of varianceOxidative stressSODinducible nitric oxide synthaseendothelial nitric oxide synthaseSuperoxide dismutaseShrHeart ratemalondialdehydePhosphate-buffered salineSpontaneously hypertensive ratsmyeloperoxidaseNitric oxidenitric oxide synthaseHematoxylin and EosinVasorelaxation
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Wenna Zhao, Jingjie Yu, Qi Su, Jinru Liang, Lina Zhao, Yongmin Zhang, Wenji Sun,