Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5839012 | Journal of Ethnopharmacology | 2012 | 10 Pages |
Abstract
⺠Extraction of KOB03 consisting of 5 different herbs and analysis of standard compound from KOB03 by HPLC analysis. ⺠Anti-allergic effects proven by allergic/inflammatory mediator release, symptom score, histopathology and signal pathway analysis in ovalbumin-induced allergic mouse and human mast cells. ⺠The working mechanism is suggested based on the in vitro experimental results by analyzing anti-allergic/inflammatory gene expressions via blocking of the ERK1/2 MAPK/NF-kappaB pathway.
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Authors
Hyo Won Jung, Jin-Ki Jung, Cheong Weon Cho, Jong-Seong Kang, Yong-Ki Park,