Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5839273 | Journal of Ethnopharmacology | 2012 | 10 Pages |
Abstract
⺠Extraction and analysis of total saponins from Panax japonicus. ⺠Cardioprotective effects proven by heart function, histopathology and biochemistry analysis. ⺠The formation mechanism is proposed based on the experimental results by analysing antioxidative and antiapoptotic and apotosis relative gene expressions.
Keywords
LVEDPTTCRT-PCRIHDSOD1SOD2CATcTnILVSPXODELSDSOD3O2–T-AOCMDAPanax japonicus2,3,5-triphenyl tetrazolium chlorideGSH-PxReal-time PCRROSMyocardial ischemiaLeft ventricularischemic heart diseaseEvaporative light scattering detectionOxidative stressoxygen free radicalsSuperoxide anion radicalsHydroxyl radicalsSODextracellular superoxide dismutaseCopper-zinc superoxide dismutasemanganese superoxide dismutaseSuperoxide dismutaseHeart rateTotal antioxidant capacityleft ventricular systolic pressureleft ventricular end-diastolic pressurecardiac troponin ILADlactate dehydrogenaseLDHmalondialdehydereal-time polymerase chain reactionCatalaseCreatine kinasehigh performance liquid chromatographyHPLCglutathione peroxidaseReactive oxygen species
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Authors
Haibo He, Jia Xu, Yuanqing Xu, Changcheng Zhang, Hongwu Wang, Yumin He, Ting Wang, Ding Yuan,