Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5839513 | Journal of Ethnopharmacology | 2011 | 8 Pages |
Abstract
The butanolic extract of Eriobotrya japonica leaves (LEJ) showed potent inhibitory effects on the inflammatory mediators including nitric oxide, iNOS, COX-2, TNF-α and IL-6 via the attenuation of NF-κB translocation to the nucleus. LEJ also exhibited excellent antinociceptive activity in both central and peripheral mechanism as a weak opioid agonist.
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Authors
Dong Seok Cha, Jae Soon Eun, Hoon Jeon,