| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5839559 | Journal of Ethnopharmacology | 2011 | 8 Pages |
Abstract
Polygalae radix (PRE) treatment inhibited 6-OHDA-induced cell damage, caspase-3 activity and the production of ROS and NO. In addition, PRE protected mesencephalic dopaminergic neurons from MPP+-induced toxicity. PRE treatment also protected dopaminergic neurons and fibers from MPTP-induced toxicity in the SNpc and ST on MPTP-induced dopaminergic neuronal damage in a mouse PD model.
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Authors
Jin Gyu Choi, Hyo Geun Kim, Min Cheol Kim, Woong Mo Yang, Youngbuhm Huh, Sun Yeou Kim, Myung Sook Oh,