Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5840692 | Journal of Pharmacological and Toxicological Methods | 2014 | 9 Pages |
Abstract
This study provides a proof-of-principle for the prediction of human TQT study results using data available early in drug development. We highlight a number of areas that need refinement to improve the method's predictive power, but the results suggest that such approaches will provide a useful tool in cardiac safety assessment.
Keywords
Related Topics
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Gary R. Mirams, Mark R. Davies, Stephen J. Brough, Matthew H. Bridgland-Taylor, Yi Cui, David J. Gavaghan, Najah Abi-Gerges,