| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5841000 | Journal of Pharmacological and Toxicological Methods | 2014 | 7 Pages |
Abstract
This study provides an in-depth comparison of the Caco-2 and MDCK-MDR1 cell based permeability assays and illustrates the utility of cell-based permeability assays in anti-malarial drug screening/development in regard to understanding transporter mediated changes in drug absorption/distribution.
Keywords
Related Topics
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Xiannu Jin, Thu-Lan Luong, Necole Reese, Heather Gaona, Vanessa Collazo-Velez, Chau Vuong, Brittney Potter, Jason C. Sousa, Raul Olmeda, Qigui Li, Lisa Xie, Jing Zhang, Ping Zhang, Greg Reichard, Victor Melendez, Sean R. Marcsisin, Brandon S. Pybus,