Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson's disease

Article ID	Journal	Published Year	Pages	File Type
5843058	Pharmacological Research	2016	47 Pages	PDF

Keywords

Tubastatin A MPTP HDAC PBST 1-methyl-4-phenylpyridinium NLS A.U.TBA DCPIP DPF PBA SDS DMB nES MS-275 PBS with 0.05% Tween 20 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 2,6-dichlorophenolindophenol 4-Phenylbutyrate BSA MPP+bovine serum albumin standard deviation days post fertilization Parkinson’s disease tyrosine hydroxylase standard error of the mean HAD blood brain barrier BBB sodium dodecyl sulfate nuclear export signal nuclear localization signal HDAC inhibitors SEM Mitochondria histone deacetylase arbitrary units Zebrafish

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Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson's disease

Authors

BrÃgida R. Pinho, Sara D. Reis, Pedro Guedes-Dias, Ana LeitÃ£o-Rocha, Clara Quintas, PatrÃcia ValentÃ£o, Paula B. Andrade, Miguel M. Santos, Jorge M.A. Oliveira,