SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy

Article ID	Journal	Published Year	Pages	File Type
5843125	Pharmacological Research	2016	59 Pages	PDF

Keywords

TEMED PAGE i.p.AGP P-gp RT-PCR Ribonuclease A DOX FBS RNAse A SDS P21 JAK-STAT CDK PBS MDR Andrographolide derivatives NCI 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide DMSO ERK1/2 MAPK MTT P-glycoprotein Reverse transcriptase PCR SOM polyacrylamide gel electrophoresis Andrographolide Cell cycle arrest Apoptosis Self Organizing Map intraperitoneal Doxorubicin Dimethyl sulfoxide sodium dodecyl sulphate fetal bovine serum Pharmacokinetics Phosphate buffered saline TRAIL Janus kinase-signal transducer and activator of transcription Multidrug resistant National Cancer Institute mitogen-activated protein kinase high performance liquid chromatography HPLC Extracellular signal-regulated kinases 1/2 cyclin dependent kinase

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SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy

Authors

Charng Choon Wong, Siang Hui Lim, Sreenivasa Rao Sagineedu, Nordin Haji Lajis, Johnson Stanslas,