Equol increases cerebral blood flow in rats via activation of large-conductance Ca2+-activated K+ channels in vascular smooth muscle cells

Article ID	Journal	Published Year	Pages	File Type
5843134	Pharmacological Research	2016	32 Pages	PDF

Keywords

Equol IbTX BaCl2 LDF 4-AP iberiotoxin KATP rCBF NOS VSMCs KHs DBP large-conductance Ca2+-activated K+ channel SBP PSS HEPES α-Subunit 5-HT 4-aminopyridine 5-hydroxy-tryptamine BSA DMSO β1 subunit bovine serum albumin ACh Acetylcholine slo analysis of variance ANOVA cerebral blood flow Regional cerebral blood flow Dimethyl sulfoxide Vascular smooth muscle cells diastolic blood pressure systolic blood pressure mean arterial pressure physiological salt solution map Nitric oxide nitric oxide synthase Voltage-gated K+ channel ATP-sensitive K+ channel Barium chloride

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Equol increases cerebral blood flow in rats via activation of large-conductance Ca2+-activated K+ channels in vascular smooth muscle cells

Authors

Wei Yu, Yan Wang, Zheng Song, Li-Mei Zhao, Gui-Rong Li, Xiu-Ling Deng,