| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5843554 | Pharmacological Research | 2015 | 11 Pages |
Abstract
In this review, we summarize GSK-3 signaling pathways and its association with neuroinflammation. Moreover, we highlight the interaction between GSK-3β and several cellular processes involved in the pathogenesis of PD, including the accumulation of α-Synuclein aggregates, oxidative stress and mitochondrial dysfunction. Finally, we discuss about GSK-3β inhibitors as a potential therapeutic strategy in PD.
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Authors
Mojtaba Golpich, Elham Amini, Fatemeh Hemmati, Norlinah Mohamed Ibrahim, Behrouz Rahmani, Zahurin Mohamed, Azman Ali Raymond, Leila Dargahi, Rasoul Ghasemi, Abolhassan Ahmadiani,