Article ID Journal Published Year Pages File Type
5843862 Pharmacological Research 2011 8 Pages PDF
Abstract
► Effect of vaspin on TNF-α-induced inflammation in vascular SMCs was examined. ► Vaspin inhibits TNF-induced monocyte adhesion to SMCs. ► Vaspin limits ICAM-1 induction by inhibiting ROS-mediated NF-κB and PKCθ activation. ► In conclusion, vaspin could play an inhibitory role on vascular SMCs inflammation.
Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
Preview
Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells
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