| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5843909 | Pharmacology & Therapeutics | 2015 | 25 Pages |
Abstract
In this new dynamic context of deep transformation in basic research and clinical management aspects of the disease, we gathered updated preclinical and clinical data in a multifaceted review encompassing the lessons learned from the past, the yet unanswered questions, and the most promising research priorities to be addressed for the next 5Â years.
Keywords
5FUFDRCrtTCACtDNAHRQOLMSCGDHIGFPSCDFSdCKFixed dose rateCA 19-9EGFα-SMA18FDG-PETECoG18F-fluorodeoxyglucose-positron emission tomographyEUSPARPDCLK1MDCTECMPFsAdenosine TriphosphateATPPancreatic ductal adenocarcinomaPDAC یا pancreatic ductal adenocarcinomaamino acidBranched-chain amino acidcarbohydrate antigen 19-9tricarboxylic acidMRIhuman equilibrative nucleoside transporter 1endoscopic retrograde cholangio-pancreatographyGOTprogression-free survivaldisease-free survivaloverall survivalBCAAImagingMagnetic resonance imagingRelative riskTargeted therapydeoxycytidine kinaseRadiotherapyPancreatic cancerpancreatic stellate cellMesenchymal stem cellsendoscopic ultrasonographyeastern cooperative oncology groupChemoradiotherapyChemotherapyepidermal growth factorInsulin-like growth factorAdapted physical activity5-fluorouracillactate dehydrogenaseLDHExtracellular matrixHematoxylin and EosinPathologyPanINAPAERCP یا endoscopic retrograde cholangiopancreatography Health-related quality of lifecirculating tumor DNAglutamate dehydrogenase
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Authors
Cindy Neuzillet, Annemilaï Tijeras-Raballand, Philippe Bourget, Jérôme Cros, Anne Couvelard, Alain Sauvanet, Marie-Pierre Vullierme, Christophe Tournigand, Pascal Hammel,