Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5856858 | Regulatory Toxicology and Pharmacology | 2014 | 11 Pages |
Abstract
The present paper demonstrates the necessity of route-specific absorption data by showing the impact of its absence on the uncertainty of the human health risk assessment using route-to-route extrapolation. Quantification of the absorption (by in vivo, in vitro or in silico methods), particularly for the starting route, is considered essential.
Keywords
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Authors
Liesbeth Geraets, Jos G.M. Bessems, Marco J. Zeilmaker, Peter M.J. Bos,