Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5866537 | American Journal of Infection Control | 2015 | 4 Pages |
Abstract
Two rapid methods of Clostridium difficile infection (CDI) diagnosis were compared between June 2012 and March 2013: a GeneXpert (Cepheid, Sunnyvale, Calif) polymerase chain reaction (PCR) test and an enzyme immunoassay (EIA). The influence of these methods on the detection of hospital-acquired CDI and identification of CDI outbreaks was evaluated. We tested 1,592 stool samples for C difficile. The GeneXpert PCR test identified 211 positive samples (68 determined to be hospital-acquired infection), whereas EIA identified 105 positive samples (36 determined to be hospital-acquired infection). The GeneXpert PCR method in contrast to the EIA method increased the detection rates of nosocomial CDI cases and contributed to the declaration of CDI outbreaks.
Keywords
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Authors
Yanal M. PhD, Justo PhD, Reza PhD, Gustavo PhD, Brenda RN, CIC, Sebastien BSc, Francisco MD, PhD,