Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5885604 | Journal of Critical Care | 2015 | 5 Pages |
Abstract
Using guideline-recommended heparin dosing without dose adjustment for temperature changes produced excessive aPTT during the cooling phase for TH patients. Reduction in the UFH dose of 43% to 54% may be required during TH. We recommend frequent aPTT monitoring during the cooling and rewarming phases to attain a desired aPTT range.
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Authors
Ryan T. PharmD, Yuk Ting Lydia PharmD, Adrian C. MD, Roger D. MD, Gregory W. MD, Ross A. MS, Narith N. PharmD,