Correlation of left ventricular systolic dysfunction determined by low ejection fraction and 30-day mortality in patients with severe sepsis and septic shock: A systematic review and meta-analysis

Article ID	Journal	Published Year	Pages	File Type
5886472	Journal of Critical Care	2014	5 Pages	PDF

Abstract

The presence of new LV systolic dysfunction associated with sepsis and defined as low LVEF is neither a sensitive nor a specific predictor of mortality. These findings are limited because of the heterogeneity and underpower of the studies. Further research into this method is warranted.

Keywords

LR−SROC MODS TTE LVEF summary receiver operating characteristic AUC LR+Systolic dysfunction echocardiography Transthoracic echocardiography intensive care unit ICU left ventricle standard error DOR Multiorgan dysfunction syndrome Septic shock confidence interval true positive false positive Mortality area under the curve false negative true negative positive likelihood ratio diagnostic odds ratio left ventricular ejection fraction ejection fraction