| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5888274 | Experimental and Molecular Pathology | 2013 | 12 Pages |
Abstract
⺠Acute endotoxemia causes macrophage accumulation of in the lung and liver. ⺠Liver macrophages are more sensitive to acute endotoxemia than lung macrophages. ⺠The effects of acute endotoxemia are blunted in mice with a nonfunctional TLR4. ⺠TLR4 is key in oxidative stress, inflammation and macrophage activation.
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Authors
Agnieszka J. Connor, Li C. Chen, Laurie B. Joseph, Jeffrey D. Laskin, Debra L. Laskin,