| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 592166 | Colloids and Surfaces A: Physicochemical and Engineering Aspects | 2015 | 11 Pages |
Abstract
- Sp-85 is a new synthetic antibiotic lipopeptide with broad spectrum activity.
- Pressure-area curves of mixed monolayers show non-ideal mixing.
- Binding to anionic liposomes results in fusion and leakage of aqueous contents.
- TEM images of antibiotic-exposed bacteria show damaged membranes.
- A mechanism of action based on bacterial membrane destabilization is proposed.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Ariadna Grau-Campistany, Montserrat Pujol, Ana M. Marqués, Ángeles Manresa, Francesc Rabanal, Yolanda Cajal,