Mitral valve regurgitation in twins: Concordance and survival

Although there is a familial aggregation of MR, the absolute risk is low, even for monozygotic cotwins to affected twins. The study found increased mortality in MR twins compared with their unaffected cotwins. Overall no excess mortality was observed in the unaffected cotwins except for first year of life and for monozygotic cotwins older than 65 years.