| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 592882 | Colloids and Surfaces A: Physicochemical and Engineering Aspects | 2014 | 11 Pages |
Abstract
- Higher PEG percentage decreases surface area while increases average pore diameter.
- The in vitro drug release was found to be biphasic (initial burst followed by slow release).
- Increasing percentage of PEG facilitates higher release and availability of the molecule in blood.
- The drug release profile establishes Level A in vitro-in vivo correlation.
- No degenerative histological changes associated with silica carriers are found.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Suparna Chakraborty, Supratim Biswas, Biswanath Sa, Satadal Das, Rajib Dey,