Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5959251 | Heart Rhythm | 2016 | 23 Pages |
Abstract
Stop-codon mutations are associated with a lower risk of cardiac events in patients with LQT1, while frameshift mutations are associated with the same risk as the majority of the missense mutations. Our data indicate functional differences between these previously considered equivalent mutation subtypes.
Keywords
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Authors
Martin H. MD, PhD, Xiaorong PhD, Arthur J. MD, Wojciech MD, PhD, Jayson BS, Scott MS, Jorgen K. MD, Wataru MD, Arthur A. MD, PhD, Christian MD, PhD, Coeli M. PhD,