Simplified Selvester Score: a practical electrocardiographic instrument to predict response to CRT

•In patients with true-LBBB, the Simplified-SSc is highly correlated to LBBB-SSc, and thus may be used as an alternative and simple instrument to identify the presence of MS.•Simplified Selvester Score has a strong association with left ventricular reverse remodeling in HF patients undergoing CRT.•Simplified Selvester Score is not associated with mortality, HF hospitalization or VT/VF.

AimsTo investigate the LBBB Selvester Scoring System (LBBB-SSc) and the Simplified-SSc prognostic impact in predicting response to CRT, all cause and cardiac mortality, heart failure (HF) hospitalizations and onset of arrhythmias in HF patients undergoing CRT.MethodsWe retrospectively evaluated LBBB-SSc and Simplified-SSc of 172 consecutive HF patients with true-LBBB who underwent CRT. Response to CRT was defined as the improvement of LVEF of at least 10% or as the reduction of LVESV of at least 15% at 6-month follow-up. Logistic regression analysis and Cox proportional hazard analysis were performed to evaluate each endpoint related risk according to LBBB-SSc and Simplified-SSc.ResultsThe LBBB-SSc and the Simplified-SSc were inversely correlated with response to CRT. Myocardial scar at both scores was independently associated to non-response to CRT. No correlation was observed between LBBB-SSc or Simplified-SSc and other endpoints.ConclusionsIn HF patients with true-LBBB, Simplified-SSc is able to predict response to CRT.