| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6020313 | Journal of Neuroimmunology | 2015 | 60 Pages |
Abstract
The peripheral pro-inflammatory stimulus aggravated the ongoing central lesion independently of the blood-brain barrier (BBB) integrity. This model allows studying the role of specific molecules and cells (neutrophils) from the innate immune system, in the relationship between central and peripheral communication, and on relapsing episodes of demyelinating lesions, along with the role of BBB integrity.
Keywords
(CSF)(GFAP)(IV)(APP)(MS)experimental autoimmune encephalomyelitisSystemic inflammationNeuroinflammationInterleukin-1βIntravenousBlood–brain barrierBlood-brain barrierCerebrospinal fluidMultiple sclerosisNeutrophilsGlial fibrillary acidic proteinβ-amyloid precursor proteinPolymorphonuclearMajor histocompatibility complex class II
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Verónica Murta, MarÃa Isabel FarÃas, Fernando Juan Pitossi, Carina Cintia Ferrari,