| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6020444 | Journal of Neuroimmunology | 2014 | 5 Pages |
Abstract
Genotype analysis of HSP70-2 (+Â 1267 A/G) polymorphism revealed a significant association between the minor allele G and presence of MS (OR:1.31, 95% CI: 1.02-1.69, PÂ =Â 0.039). In addition, Hsp70-2 protein content in vitro from PBMC was significantly lower in MS patients with GG genotype compared to AA genotype, indicating an implication of the G allele of HSP70-2 gene polymorphism in the development of MS.
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Authors
Chiara Boiocchi, Cecilia Osera, Maria Cristina Monti, Ottavia Eleonora Ferraro, Stefano Govoni, Mariaclara Cuccia, Cristina Montomoli, Alessia Pascale, Roberto Bergamaschi,