| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6020681 | Journal of Neuroimmunology | 2012 | 7 Pages |
Abstract
We conclude that the expression of HGF within the CNS is reflective of disease activity in MS and this may be due to decreased induction of HGF by CCL2. Furthermore, the decreased HGF associated with active disease may potentially contribute to reduced stimulation for remyelination and the occurrence of shadow plaques frequently seen in MS patients. Our results merit further validation to establish whether CSF HGF is a biomarker for MS disease activity.
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Authors
Andre Michael Müller, Esther Jun, Hana Conlon, Saud Ahmed Sadiq,