Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6020705 | Journal of Neuroimmunology | 2013 | 6 Pages |
Abstract
⺠Chemokine signaling via CCR4/CCR6 receptors play a role in the development of EAE. ⺠IL-6 and IL-17 production are promoted by CCR4/CCR6 signaling. ⺠CCR4/CCR6 expression by T lymphocytes is presumably of key importance. ⺠CCR6 and CCR4 might be a therapeutic target of multiple sclerosis.
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Authors
Kota Moriguchi, Katsuichi Miyamoto, Noriko Tanaka, Osamu Yoshie, Susumu Kusunoki,