Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6021109 | Journal of Neuroimmunology | 2011 | 12 Pages |
Abstract
In conclusion, these results suggest that T. gondii modulates gene expression of brain endothelial cells to promote its own migration through the blood-brain barrier in a 'Trojan horse' manner. Cells expressing CD11b either with or without CD11c are likely candidate cells for the intracellular transport of T. gondii across the BBB. T. gondii type I and type II strains induced similar migration patterns of antigen-presenting cells across the in vitro BBB.
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Authors
Sabrina M. Lachenmaier, Mária A. Deli, Markus Meissner, Oliver Liesenfeld,