Simultaneous determination of epinephrene and paracetamol at copper-cobalt oxide spinel decorated nanocrystalline zeolite modified electrodes

•Nanocrystalline MCo2O4 materials were prepared.•CuCo2O4/nanocrystalline ZSM-5 nanocomposite was prepared.•Electrochemical sensors based on these materials were fabricated.•Simultaneous nanomolar detection of epinephrine and paracetamol was achieved.•Commercial pharmaceutical samples were investigated.

In this study, CuCo2O4 and CuCo2O4 decorated nanocrystalline ZSM-5 materials were prepared. For comparative study, a series of MCo2O4 spinels were also prepared. Materials were characterized by the complementary combination of X-ray diffraction, N2-adsorption, UV–visible, and electron microscopic techniques. A simple and rapid method for the simultaneous determination of paracetamol and epinephrine at MCo2O4 spinels modified electrodes is presented in this manuscript. Among the materials investigated in this study, CuCo2O4 decorated nanocrystalline ZSM-5 exhibited the highest electrocatalytic activity with excellent stability, sensitivity, and selectivity. Analytical performance of the sensor was demonstrated in the determination of epinephrine and paracetamol in the commercial pharmaceutical samples.

Graphical abstractNanocrystalline zeolite supported cobalt oxide spinels based efficient electrochemical sensor for the simultaneous determination of epinephrene and paracetamol.Figure optionsDownload full-size imageDownload high-quality image (220 K)Download as PowerPoint slide